Associated Conditions

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If you are experiencing fatigue or symptoms that you feel may be post-exertional malaise (PEM), please review our information on stop rest pace and talk to your doctor about your concerns.

Fibromyalgia
 

There is agreement within the medical community that fibromyalgia and ME/CFS are similar conditions, and may be related. However, the major difference between the two conditions is the predominant symptom.

Orthostatic intolerance (OI)

There are a number of different forms of orthostatic intolerance, these are

  • Postural Orthostatic Tachycardia Syndrome (POTS)
  • Orthostatic hypotension (OH)
  • Neurally mediated hypotension (NHH)
Mast cell activation syndrome (MCAS)
 

Mast cell activation syndrome (MCAS) is often linked with hypermobile Ehlers–Danlos syndrome (hEDS), postural orthostatic tachycardia syndrome (POTS) and ME/CFS. It may also be involved in the symptoms of acute and long COVID.

Ehlers-Danlos syndrome (EDS)
 

Ehlers-Danlos syndrome (EDS) refers to a group of genetic disorders that involve connective tissue. It is inherited and can affect any part of the body.

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